How do I correct for background noise in my blots?

You can use the `analyze_band_densities` tool. Provide the raw intensities and the background intensities for each band to get the corrected values.

How can I account for unequal protein loading?

Use the `normalize_protein_expression` tool. By providing both your target protein data and your loading control data (like GAPDH or Actin), the tool calculates relative expression.

Can I compare multiple experimental groups?

Yes. You can use `calculate_fold_change` to see the magnitude of change relative to a control, and `evaluate_statistical_significance` to check if those differences are statistically meaningful.

Western Blot Quantification MCP Connector for Claude

A+

Quantify protein expression from western blot data using densitometry and statistical analysis.

4 tools Official Updated Oct 1, 2026 Official Vinkius Partner

More Details Connect to Claude

This MCP server provides a complete suite of tools for analyzing western blot results. It allows AI agents to perform background correction using analyze_band_densities, normalize protein levels via normalize_protein_expression, calculate group-wise changes with calculate_fold_change, and determine statistical significance using evaluate_statistical_significance. It transforms raw band intensities into meaningful biological insights like fold change and p-values.

western-blotproteindensitometryquantificationstatistics

Connect to Claude

Subscribe on Vinkius, then add this connector to Claude.ai or Claude Code.

① Claude.ai (web app)

Go to Settings → Connectors → Add custom connector
Paste the MCP endpoint URL below

https://edge.vinkius.com/vk_preview_4KOvUoSKEHEuudlzLKG9xTF08mY0jXNg52L2l3PM/mcp

② Claude Code (terminal)

claude mcp add --transport http western-blot-quantification https://edge.vinkius.com/vk_preview_4KOvUoSKEHEuudlzLKG9xTF08mY0jXNg52L2l3PM/mcp

③ Claude Desktop

Add to claude_desktop_config.json:

{
  "mcpServers": {
    "western-blot-quantification": {
      "url": "https://edge.vinkius.com/vk_preview_4KOvUoSKEHEuudlzLKG9xTF08mY0jXNg52L2l3PM/mcp"
    }
  }
}

Get full access on Vinkius

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