Protein Molecular Weight Calculator

Protein Molecular Weight Calculator MCP Connector for Claude

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Calculate protein mass, extinction coefficient, and isoelectric point from sequences or compositions.

4 tools Official Updated Oct 1, 2026 Official Vinkius Partner

This MCP server provides specialized biochemical tools for protein characterization. Use calculate_sequence_properties to derive a full suite of physical properties including molecular weight, UV absorption, and pI from a single-letter amino acid sequence. For mass calculations based on residue counts, use calculate_composition_mass. You can also isolate specific properties using get_extinction_coefficient for UV absorption at 280nm or estimate_isoelectric_point to find the neutral pH of a protein sequence. The tools account for post-translational modifications to ensure accurate biochemical modeling.

proteinmolecular-weightbiochemistrypiamino-acid

4 tools expose this connector's capabilities to your AI agent.

calculate_composition_mass

Calculates the total molecular weight based only on the counts of each amino acid present

calculate_sequence_properties

Calculates a full suite of physical properties for a specific protein sequence

estimate_isoelectric_point

Estimates the pH at which the protein is electrically neutral

get_extinction_coefficient

Determines the UV absorption capability of a protein at 280nm

See how to talk to your AI agent using Protein Molecular Weight Calculator.

What is the molecular weight and pI of the sequence MKWVTFISLLFLFSSAYSRGVFRR?

The protein has a molecular weight of approximately 2543.2 Da and an estimated isoelectric point of 5.2.

Calculate the mass for a composition of 10 Alanine (A) and 5 Glycine (G).

The total molecular weight for this composition is 185.15 Da.

What is the extinction coefficient for the sequence WYYW?

The molar extinction coefficient (ε280) for the sequence WYYW is 12450.5.

You can use the `calculate_composition_mass` tool by providing a JSON mapping of amino acid single-letter codes to their respective counts.

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