Validation Parameter Calculator

Validation Parameter Calculator MCP Connector for Claude

A+

Calculates ICH Q2 analytical method validation parameters like accuracy, precision, and linearity.

4 tools Official Updated Oct 1, 2026 Official Vinkius Partner

This MCP server provides specialized tools for pharmaceutical and chemical method validation following ICH Q2 guidelines. It allows AI agents to perform complex analytical calculations including calculate_accuracy for percent recovery, calculate_precision for repeatability and intermediate precision, calculate_linearity_and_range for linear regression analysis, and evaluate_method_suitability to verify robustness and system suitability against defined thresholds.

ich-q2analytical-chemistrymethod-validationaccuracyprecision

4 tools expose this connector's capabilities to your AI agent.

calculate_accuracy

Calculates the accuracy of the method via percent recovery

calculate_linearity_and_range

Validates the linear relationship between concentration and response

calculate_precision

Evaluates the precision of the method across different levels

evaluate_method_suitability

Checks if the method meets pre-defined acceptance criteria for robustness and system suitability

See how to talk to your AI agent using Validation Parameter Calculator.

Calculate the accuracy for measurements [98.5, 101.2, 99.8] with a true value of 100.

The percent recovery is 99.83%.

Check the linearity for concentrations [10, 20, 30] and responses [5.1, 10.2, 14.9].

The correlation coefficient is 0.999, confirming a strong linear relationship.

Evaluate if the method is suitable with suitability results [0.98, 1.02] and robustness variations [0.01, 0.02] using thresholds {"suitability": 0.05, "robustness": 0.05}.

The method is suitable as all parameters fall within the specified acceptance thresholds.

The calculations are designed to align with the International Council for Harmonisation (ICH) Q2 guidelines for analytical procedure validation.

Related Connectors