MCP For Claude Marketplace
Organic Synthesis Planner

Organic Synthesis Planner MCP Connector for Claude

A+

Automated retrosynthetic analysis and synthetic route planning for organic molecules.

4 tools Official Updated Oct 1, 2026 Official Vinkius Partner
More Details Connect to Claude

This MCP server provides an automated reasoning engine for organic chemistry. It decomposes complex target molecules into viable synthetic pathways using retrosynthetic logic. Users can use plan_synthetic_routes to generate complete pathways from starting materials, evaluate_route_viability to check for chemical conflicts, get_intermediate_properties to analyze molecular characteristics, and suggest_protecting_groups to identify necessary protection strategies for specific transformations.

retrosynthesisorganic-chemistrymolecular-designchemical-synthesischeminformatics

4 tools expose this connector's capabilities to your AI agent.

evaluate_route_viability

Analyzes a specific proposed route to check for chemical conflicts and feasibility

get_intermediate_properties

Retrieves the structural and chemical characteristics of a specific intermediate in a planned pathway

plan_synthetic_routes

Proposes one or more complete pathways to reach the target molecule from the provided starting materials

suggest_protecting_groups

Identifies which functional groups in a molecule require protection to allow a specific transformation to occur

See how to talk to your AI agent using Organic Synthesis Planner.

Plan a synthetic route for Aspirin (CC(=O)OC1=CC=CC=C1C(=O)O) starting from Salicylic acid (C1=CC=C(C(C(=O)O)O)C=C1).

The synthesis of Aspirin from Salicylic acid involves the acetylation of the phenolic hydroxyl group using acetic anhydride in the presence of an acid catalyst.

What are the properties of the intermediate with SMILES C1=CC=C(C=C1)C(=O)O?

The intermediate is Benzoic acid, which has a molecular weight of approximately 122.12 g/mol and contains a carboxylic acid functional group.

Check if this route is viable: [route_data_here]

The route is chemically viable as all reagents are compatible with the functional groups present in the intermediates.

You can use the `plan_synthetic_routes` tool by providing the SMILES notation of your target molecule and a list of available starting materials.

Related Connectors

Chemical Substitution Analysis

Chemical Substitution Analysis MCP

4 tools Official

Identify safer chemical alternatives and evaluate implementation feasibility.

A+ View details →
Organic Compound Nomenclature

Organic Compound Nomenclature MCP

4 tools Official

Precise IUPAC naming and chemical property analysis for organic molecules.

A+ View details →
Main Group Chemistry Predictor

Main Group Chemistry Predictor MCP

4 tools Official

Predict reactivity, stability, and reaction outcomes for main group elements.

A+ View details →
Limiting Reagent Yield Calculator

Limiting Reagent Yield Calculator MCP

4 tools Official

A precision stoichiometry engine for determining limiting reactants, theoretical yields, and efficiency metrics.

A+ View details →