MCP For Claude Marketplace
EPA Computational Toxicology

EPA Computational Toxicology MCP Connector for Claude

A+

Access the US EPA's CompTox Chemicals Dashboard data — search for chemicals, properties, hazard summaries, and exposure data.

10 tools Official Updated Jun 28, 2026 Official Vinkius Partner
More Details Connect to Claude

Connect to the US Environmental Protection Agency's (EPA) Center for Computational Toxicology and Exposure (CCTE) and explore a massive repository of chemical data through natural conversation.

What you can do

  • Chemical Search — Find substances by name, CAS Registry Number (CASRN), or DTXSID
  • Physicochemical Properties — Retrieve melting points, boiling points, logP, and water solubility
  • Hazard Assessments — Access toxicity values, NOAELs, and points-of-departure from ToxValDB
  • Exposure Predictions — Explore predicted exposure levels and product use categories via ExpoCast and CPDat
  • Bioactivity Screening — Analyze ToxCast/Tox21 high-throughput screening results for thousands of assays
  • Environmental Fate — Check persistence, transport, and biodegradation metrics

How it works

  1. Subscribe to this server
  2. Enter your free EPA API Key (request it by emailing ccte_api@epa.gov)
  3. Start investigating chemical safety and properties directly from your agent

This tool is essential for toxicologists, environmental scientists, and regulatory professionals who need instant access to high-quality chemical data.

Who is this for?

  • Toxicologists — quickly gather hazard and bioactivity data for risk assessments
  • Environmental Scientists — analyze fate and transport properties of contaminants
  • Product Safety Teams — check chemical exposure and product use profiles
  • Researchers — retrieve identifiers and synonyms for chemical lists
toxicologychemical-dataexposure-assessmentcasrnphysicochemical-propertieshazard-summary

10 tools expose this connector's capabilities to your AI agent.

get_bioactivity_summary

Retrieve a summary of high-throughput screening results from ToxCast/Tox21 assays

get_chemical_details

Get comprehensive metadata and identification details for a specific chemical using its DTXSID

get_chemical_lists

Identify which chemical lists (regulatory, research, or commercial) this chemical belongs to

get_chemical_synonyms

Retrieve all known synonyms and alternative names for a specific chemical

get_exposure_summary

Retrieve predicted exposure levels and product use data (ExpoCast/CPDat)

get_fate_and_transport

Retrieve environmental fate and transport data (e.g., half-life, bioconcentration)

get_hazard_summary

Retrieve a summary of toxicity values and hazard assessment data from ToxValDB

get_physicochemical_properties

Retrieve predicted and experimental physicochemical properties (e.g., melting point, logP, solubility) for a chemical

search_chemical_by_casrn

Search for chemicals by their CAS Registry Number (CASRN)

search_chemical_by_name

Search for chemicals by common, IUPAC, or synonym names in the EPA CompTox database

See how to talk to your AI agent using EPA Computational Toxicology.

Search for the chemical properties of Bisphenol A.

I've found Bisphenol A (DTXSID7020182). Its properties include a melting point of 158°C, water solubility of 120 mg/L, and a logP of 3.32.

What is the hazard summary for CAS 80-05-7?

For CAS 80-05-7, the hazard summary indicates concerns for endocrine disruption and reproductive toxicity, with ToxValDB listing several points-of-departure for developmental endpoints.

Find predicted exposure data for DTXSID7020182.

Retrieving exposure data... Predicted geometric mean intake for this substance is 1.2e-4 mg/kg-bw/day. Common product categories include 'Food Packaging' and 'Polymer production'.

You must send an email to `ccte_api@epa.gov` to request an individual API key. The key is usually issued free of charge for research and professional use.

Related Connectors

CO

Conda (Anaconda.org) MCP

8 tools

Enable your AI agent to search packages, inspect metadata, and explore channels on Anaconda.org via the Conda API.

A+ View details →
FA

Fantastical MCP

10 tools Official

Manage calendars via Fantastical — create events using natural language, handle scheduling openings and proposals, and monitor connected accounts directly from any AI agent.

A+ View details →
LO

LocalAI MCP

19 tools Official

Run LLMs, generate images, and process audio locally. OpenAI-compatible API for your own hardware.

A+ View details →
US

Uselessfacts MCP

3 tools Official

Access a vast database of quirky, useless facts to entertain, break the ice, or learn something new every day.

F View details →